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Medium achievements start to introduce more game knowledge requirement, as well as the need for better gear.
There are 40 total achievements for this category.
| Achievement | Description |
|---|---|
| Atehereal Tortoise II | Kill 50 Aethereal Tortoise. |
| Avengers II | Complete 25 Avengers Arcade. |
| Bird Watcher II | Open 5 Bird's Nests. |
| Blacksmith II | Find 25 Blacksmith's Bounty. |
| Cerberus I | Kill 50 Cerberus. |
| Clue Hunter II | Complete 50 Clue Scrolls. |
| Crimson Chin I | Kill 50 Crimson Chin. |
| D.C. Universe II | Complete 50 D.C. Universe Arcade. |
| Demonic Gorillas I | Kill 50 Demonic Gorillas. |
| Divine Tree Spirits II | Kill 10 Divine Tree Spirits. |
| Elemental Fury Staff | Equip an Elemental Fury Staff. |
| Avengers II | Kill 20 Essenceborn Colossus. |
| Green Thumb II | Harvest 250 herbs. |
| Grinder Points II | Grind 250,000 Grinder Points. |
| Grotesque Guardians I | Kill 25 Grotesque Guardians. |
| Group Slayer II | Complete 5 Group Slayer Tasks. |
| King of the Sea II | Kill 100 Poseidon. |
| Master of Fishing II | Complete 10 easy fishing tasks. |
| Masterwork Mayhem II | Kill 100 Masterwork Warriors. |
| NPC Killcount II | Achieve 10,000 NPC Kills. |
| Omen Slayer II | Kill 100 Cursed Omen. |
| Pepe Slayer II | Kill 25 Vote Bosses. |
| Politician II | Claim 30 Vote Redeem Codes. |
| Pyromaniac II | Offer 500 logs to the Bonfire. |
| Quiz Master II | Answer 10 Trivia Question. |
| Runecrafting II | Craft 10,000 runes. |
| Secured the Bag II | Obtain 500 Money Bags from the Money Tree. |
| Slayer Keys II | Open 10,000 Slayer Keys. |
| Slayer Master I | Achieve Prestige 1 Slayer. |
| Slayer Master II | Achieve Prestige 2 Slayer. |
| Slayer Master III | Achieve Prestige 3 Slayer. |
| Slayer Master IV | Achieve Prestige 4 Slayer. |
| Slayer Superior I | Complete 25 Slayer Superiors. |
| Tempoross II | Loot 100 Permits from Tempoross Pool. |
| The Nightmare I | Kill 25 of The Nightmare Boss. |
| Theatre of Blood II | Loot Theatre of Blood chest 25 times. |
| Woodcutting Tasks II | Complete 10 Woodcutting Tasks. |